Comparison of the Effects of Metoprolol and Bisoprolol on Lipid and Glucose Profiles in Cardiovascular Patients.

Authors :: Almeman AA
Beshir YA
Aldosary AH
Source :: Current drug safety [Curr Drug Saf] 2019; Vol. 14 (1), pp. 27-30.
Publication Year :: 2019
Abstract: Background: Cardioselective beta-blockers may affect glucose or lipid profiles.<br />Objective: We sought to compare the effects of two beta-blockers, metoprolol and bisoprolol, as the most commonly used drugs in cardiology, on glucose and lipid profiles in patients with cardiovascular diseases.<br />Methods: We conducted a retrospective cross-sectional matched study at Prince Sultan Cardiac Center in Burydah in August 2017. Patient records were screened, and adult patients with cardiovascular disorders who were treated with a stable dose of metoprolol or bisoprolol were included. Parameters related to glucose and lipid metabolism were compared using the Student's t-test between the two groups.<br />Results and Conclusion: The metoprolol and bisoprolol arms included 204 and 200 patients, respectively.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Subjects :: Antihypertensive Agents adverse effects
Antihypertensive Agents therapeutic use
Bisoprolol adverse effects
Cross-Sectional Studies
Electrocardiography drug effects
Female
Humans
Male
Metoprolol adverse effects
Middle Aged
Retrospective Studies
Treatment Outcome
Bisoprolol therapeutic use
Cardiovascular Diseases blood
Cardiovascular Diseases drug therapy
Glucose metabolism
Lipids blood
Metoprolol therapeutic use

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