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Wound Pathogens: Investigating Antimicrobial Activity of Commercial Essential Oil Combinations against Reference Strains.
- Source :
-
Chemistry & biodiversity [Chem Biodivers] 2018 Dec; Vol. 15 (12), pp. e1800405. Date of Electronic Publication: 2018 Dec 17. - Publication Year :
- 2018
-
Abstract
- This study aimed to determine the antimicrobial activity of 247 essential oil combinations against the reference strains of wound pathogens. Essential oil combinations were investigated for antimicrobial activity against five pathogens. The minimum inhibitory concentration (MIC) assay was used and the fractional inhibitory concentration index (ΣFIC) calculated to determine interactions between selected oils. Twenty-six combinations displayed broad-spectrum antimicrobial activity against all five reference strains and several displayed synergy against more than one pathogen. The combination of Santalum austrocaledonicum (sandalwood) with Commiphora myrrha (myrrh) displayed noteworthy antimicrobial activity against all five reference strains and synergy against four (MIC values 0.03-1.00 mg/ml and ΣFIC values 0.19-1.00 mg/ml) pathogens. No antagonism was observed. Santalum spp. and Vetiveria zizanioides essential oils contributed the most to antimicrobial activity in combination. Essential oil combinations are presented as a viable option in wound therapy.<br /> (© 2018 Wiley-VHCA AG, Zurich, Switzerland.)
- Subjects :
- Anti-Infective Agents pharmacology
Chrysopogon chemistry
Chrysopogon metabolism
Commiphora chemistry
Commiphora metabolism
Drug Resistance, Bacterial drug effects
Drug Synergism
Escherichia coli drug effects
Microbial Sensitivity Tests
Oils, Volatile pharmacology
Pseudomonas aeruginosa drug effects
Santalum chemistry
Santalum metabolism
Staphylococcus aureus drug effects
Anti-Infective Agents chemistry
Oils, Volatile chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1612-1880
- Volume :
- 15
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Chemistry & biodiversity
- Publication Type :
- Academic Journal
- Accession number :
- 30362637
- Full Text :
- https://doi.org/10.1002/cbdv.201800405