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DSM-5 cannabis withdrawal syndrome: Demographic and clinical correlates in U.S. adults.
- Source :
-
Drug and alcohol dependence [Drug Alcohol Depend] 2019 Feb 01; Vol. 195, pp. 170-177. Date of Electronic Publication: 2018 Oct 22. - Publication Year :
- 2019
-
Abstract
- Background: Cannabis withdrawal syndrome (CWS) was newly added to the Diagnostic and Statistical Manual of Mental Disorders in its most recent edition, DSM-5. With cannabis use increasing among U.S. adults, information is needed about the prevalence and correlates of DSM-5 CWS in the general population. This study presents nationally representative findings on the prevalence, sociodemographic and clinical correlates of DSM-5 CWS among U.S. adults.<br />Method: Participants ≥18 years were interviewed in the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) in 2012-2013. Among the sub-sample of frequent cannabis users in the prior 12 months (≥3 times a week; N = 1527), the prevalence and demographic and clinical correlates of DSM-5 CWS were examined.<br />Results: In frequent cannabis users, the prevalence of CWS was 12.1%. The most common withdrawal symptoms among those with CWS were nervousness/anxiety (76.3%), hostility (71.9%), sleep difficulty (68.2%) and depressed mood (58.9%). CWS was associated with significant disability (p < 0.001), and with mood disorders (adjusted odds ratios [aOR] = 1.9-2.6), anxiety disorders (aOR = 2.4-2.5), personality disorders (aOR = 1.7-2.2) and family history of depression (aOR = 2.5) but not personal history of other substance use disorders or family history of substance use problems.<br />Conclusions: CWS is highly comorbid and disabling. Its shared symptoms with depressive and anxiety disorders call for clinician awareness of CWS and the factors associated with it to promote more effective treatment among frequent cannabis users.<br /> (Copyright © 2018. Published by Elsevier B.V.)
- Subjects :
- Adolescent
Adult
Aged
Anxiety Disorders diagnosis
Anxiety Disorders epidemiology
Anxiety Disorders psychology
Cannabis
Comorbidity
Female
Humans
Male
Marijuana Abuse epidemiology
Marijuana Smoking adverse effects
Marijuana Smoking epidemiology
Marijuana Smoking psychology
Middle Aged
Personality Disorders diagnosis
Personality Disorders epidemiology
Personality Disorders psychology
Substance Withdrawal Syndrome epidemiology
United States epidemiology
Young Adult
Diagnostic and Statistical Manual of Mental Disorders
Health Surveys methods
Marijuana Abuse diagnosis
Marijuana Abuse psychology
Substance Withdrawal Syndrome diagnosis
Substance Withdrawal Syndrome psychology
Subjects
Details
- Language :
- English
- ISSN :
- 1879-0046
- Volume :
- 195
- Database :
- MEDLINE
- Journal :
- Drug and alcohol dependence
- Publication Type :
- Academic Journal
- Accession number :
- 30361043
- Full Text :
- https://doi.org/10.1016/j.drugalcdep.2018.09.005