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[With the Characteristics of Chronic Pain Patients, Can the Therapeutic Effect of Antidepressant Duloxetine be Predicted?].
- Source :
-
Masui. The Japanese journal of anesthesiology [Masui] 2016 Oct; Vol. 65 (10), pp. 1005-1008. - Publication Year :
- 2016
-
Abstract
- Background: Duloxetine, an antidepressant, is used for treatment of pain, but the factors related to its effectiveness are not well known, and therefore we have performed a retrospective study.<br />Methods: Over a 22-month period from June 2012 patients with pain lasting for 3 months or more, with an NRS of 4 or higher, and given duloxetine within 3 months from their first diagnosis, were extracted from the medical records. These patients were compared and studied regarding their scores of the HADS (hos- pital anxiety and depression scale) at the time of first visit, duration of the disease, type of patient, and treat- ment effect after 1 month.<br />Results: The subjects were 61 patients, and they were categorized based on the presence of anxiety, the presence of dysphoria whether from organic or inor- ganic condition, and the duration of the disease, and no significant difference in the effectiveness of duloxetine was found.<br />Conclusions: Duloxetine had an overall effectiveness of 50.8%, regardless of the presence of anxiety or depression, the duration of the disease and the type of diseases.
Details
- Language :
- Japanese
- ISSN :
- 0021-4892
- Volume :
- 65
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Masui. The Japanese journal of anesthesiology
- Publication Type :
- Academic Journal
- Accession number :
- 30358274