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Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia: Clinical Validity and Psychometric Properties.
- Source :
-
Dementia and geriatric cognitive disorders [Dement Geriatr Cogn Disord] 2018; Vol. 46 (3-4), pp. 243-252. Date of Electronic Publication: 2018 Oct 23. - Publication Year :
- 2018
-
Abstract
- Background: We evaluated the psychometric proprieties of the Screening for Aphasia in NeuroDegeneration (SAND) battery in Italian primary progressive aphasia (PPA) and movement disorder (MD) patients.<br />Methods: The sample included 30 consecutive PPA and 45 MD patients who completed the SAND battery together with a clinical interview and a neurological/neuropsychological examination and 130 healthy controls (HC).<br />Results: The SAND battery showed good internal consistency and good convergent and divergent validity. receiver operating characteristic analysis revealed an area under the curve of 0.978 for PPA versus HC and of 0.786 for PPA versus MD. A cutoff ≥3 gave a sensitivity of 0.933% and a specificity of 0.946% for discriminating PPA versus HC, whereas a cutoff ≥5 gave a sensitivity of 0.767% and a specificity of 0.667% for discriminating PPA versus MD.<br />Conclusion: These results indicate that the SAND battery is an adequate, reliable, and valid diagnostic tool for PPA.<br /> (© 2018 S. Karger AG, Basel.)
- Subjects :
- Aged
Female
Humans
Italy
Male
Mass Screening methods
Middle Aged
Neurologic Examination methods
Neuropsychological Tests
Psychometrics methods
ROC Curve
Reproducibility of Results
Speech Production Measurement methods
Aphasia, Primary Progressive diagnosis
Aphasia, Primary Progressive etiology
Movement Disorders diagnosis
Movement Disorders etiology
Neurodegenerative Diseases complications
Subjects
Details
- Language :
- English
- ISSN :
- 1421-9824
- Volume :
- 46
- Issue :
- 3-4
- Database :
- MEDLINE
- Journal :
- Dementia and geriatric cognitive disorders
- Publication Type :
- Academic Journal
- Accession number :
- 30352431
- Full Text :
- https://doi.org/10.1159/000492632