Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma.

Authors :: Ravi K
Codipilly DC
Sunjaya D
Fang H
Arora AS
Katzka DA
Source :: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2019 Aug; Vol. 17 (9), pp. 1902-1903.e1. Date of Electronic Publication: 2018 Oct 17.
Publication Year :: 2019
Abstract: Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells. <superscript>1-3</superscript> Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports. <superscript>4,5</superscript> We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.<br /> (Copyright © 2019 AGA Institute. Published by Elsevier Inc. All rights reserved.)

Language :: English
ISSN :: 1542-7714
Volume :: 17
Issue :: 9
Database :: MEDLINE
Journal :: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Publication Type :: Academic Journal
Accession number :: 30342260
Full Text :: https://doi.org/10.1016/j.cgh.2018.10.018

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