Back to Search Start Over

Survival after diagnosis of hypertension in cats attending primary care practice in the United Kingdom.

Authors :
Conroy M
Chang YM
Brodbelt D
Elliott J
Source :
Journal of veterinary internal medicine [J Vet Intern Med] 2018 Nov; Vol. 32 (6), pp. 1846-1855. Date of Electronic Publication: 2018 Oct 13.
Publication Year :
2018

Abstract

Background: Hypertension is common in older cats. There is limited evidence for predictors of survival after diagnosis.<br />Hypothesis/objectives: Investigate blood pressure assessment (BPA) and hypertension diagnosis in cats attending UK primary care practices (PCPs) and factors that influence survival.<br />Animals: Cats (347 889) attending 244 UK PCPs enrolled in the VetCompass program between January 1, 2012, and December 31, 2013. Cats identified as hypertensive (282) were included in descriptive and survival analyses.<br />Methods: All electronic patient records (EPRs) were searched to identify cats that potentially had received BPA. EPRs were read in detail to identify those that had BPA. The proportion that received BPA was evaluated using a stratified analysis and the incidence of hypertension estimated. A retrospective cohort study was used to investigate survival after diagnosis (Cox proportional hazard model).<br />Results: Estimated incidence risk was 19.5% (95% confidence interval [CI], 17.5-21.6) from the estimated 1.34% (1.30%-1.38%) of cats that received BPA. Few cats had BPA more than once after diagnosis (median, 1; interquartile range [IQR], 0-3), with only 9.9% of diagnosed hypertensive cats having urine protein:creatinine ratio determined. Cats diagnosed as a result of monitoring of pre-existing disease had improved survival (hazard ratio [HR], 0.58; 95% CI, 0.37-0.89; P = .01) compared to cats diagnosed after clinical signs were recognized. Cats that had an amlodipine dose change had improved survival (HR, 0.56; 95% CI, 0.36-0.87; P = .01) compared to those with no dose change.<br />Conclusions and Clinical Importance: These data suggest improved blood pressure monitoring in clinical practice may decrease the morbidity associated with hypertension.<br /> (© 2018 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.)

Details

Language :
English
ISSN :
1939-1676
Volume :
32
Issue :
6
Database :
MEDLINE
Journal :
Journal of veterinary internal medicine
Publication Type :
Academic Journal
Accession number :
30315661
Full Text :
https://doi.org/10.1111/jvim.15307