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Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores.
- Source :
-
Nature communications [Nat Commun] 2018 Oct 05; Vol. 9 (1), pp. 4085. Date of Electronic Publication: 2018 Oct 05. - Publication Year :
- 2018
-
Abstract
- Crucial steps in the miniaturisation of biosensors are the conversion of a biological signal into an electrical current as well as the direct sampling of bodily fluids. Here we show that protein sensors in combination with a nanopore, acting as an electrical transducer, can accurately quantify metabolites in real time directly from nanoliter amounts of blood and other bodily fluids. Incorporation of the nanopore into portable electronic devices will allow developing sensitive, continuous, and non-invasive sensors for metabolites for point-of-care and home diagnostics.
Details
- Language :
- English
- ISSN :
- 2041-1723
- Volume :
- 9
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Nature communications
- Publication Type :
- Academic Journal
- Accession number :
- 30291230
- Full Text :
- https://doi.org/10.1038/s41467-018-06534-1