Back to Search
Start Over
Obsessive-compulsive symptom dimensions: Association with comorbidity profiles and cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder.
- Source :
-
Psychiatry research [Psychiatry Res] 2018 Dec; Vol. 270, pp. 317-323. Date of Electronic Publication: 2018 Sep 22. - Publication Year :
- 2018
-
Abstract
- Our aims were to examine: (1) classes of comorbid disorders in a sample of children and adolescents with Obsessive-Compulsive Disorder (OCD), (2) how these classes relate to obsessive-compulsive symptom dimensions, and (3) the extent to which obsessive-compulsive symptom dimensions predict Cognitive-Behavioral Therapy (CBT) outcome. Participants (N = 269) were assessed with the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS-PL) and the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS). Latent Class Analysis (LCA) was used to identify comorbidity classes. Regression analyses were used to evaluate symptom dimensions as predictors of treatment outcome and their relation to comorbidity classes. Comorbidity was included in the treatment outcome analyses as it can affect outcome. Comorbidity was best categorized by a three-class model and each class was distinctively correlated with the OCD symptom dimensions. Higher scores on the symmetry/hoarding factor increased the chance of responding to CBT by an odds ratio of 1.56 (p = 0.020) when controlled for age, gender, and comorbidity class. The harm/sexual factor (p = 0.675) and contamination/cleaning factor (p = 0.122) did not predict CBT outcome. Three clinically relevant comorbidity subgroups in pediatric OCD were identified. Patients who exhibited higher levels of symmetry/hoarding dimension were more prone to respond to CBT.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)
- Subjects :
- Adolescent
Child
Cognitive Behavioral Therapy
Comorbidity
Female
Hoarding epidemiology
Hoarding therapy
Humans
Logistic Models
Male
Obsessive-Compulsive Disorder epidemiology
Obsessive-Compulsive Disorder therapy
Odds Ratio
Prognosis
Sexual Behavior
Treatment Outcome
Hoarding psychology
Obsessive-Compulsive Disorder psychology
Subjects
Details
- Language :
- English
- ISSN :
- 1872-7123
- Volume :
- 270
- Database :
- MEDLINE
- Journal :
- Psychiatry research
- Publication Type :
- Academic Journal
- Accession number :
- 30290317
- Full Text :
- https://doi.org/10.1016/j.psychres.2018.09.054