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Sequences of Sequences: Spatial Organization of Coded Matter through Layer-by-Layer Assembly of Digital Polymers.

Authors :
Szweda R
Tschopp M
Felix O
Decher G
Lutz JF
Source :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2018 Nov 26; Vol. 57 (48), pp. 15817-15821. Date of Electronic Publication: 2018 Nov 07.
Publication Year :
2018

Abstract

A library of 16 digitally encoded polyanions was used in a layer-by-layer (LbL) polyelectrolyte assembly to nanofabricate thin films containing digitally coded strata. The polyanions were digital polyphosphodiesters (d-PPDE) prepared via an automated phosphoramidite process. Each component of the library contained 10 bytes of ASCII-encoded text (i.e. 80 coded monomers); thus the entire library allows the writing of a full sentence, which can be stored in a multilayer film as a sequence of sequences. To prepare fully segregated digital domains, non-coded layers composed of poly(allylamine hydrochloride) (PAH)/poly(sodium 4-styrenesulfonate) (PSS) were included between the d-PPDE coded layers as an intermediate barrier. Detailed analysis of the film homogeneity indicated formation of 70 nm-thick films in which digital layers are kept apart from another by non-coded interlayers. As a result, the sequence-coded polymer library could be piled-up in a defined sequence of layers.<br /> (© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Details

Language :
English
ISSN :
1521-3773
Volume :
57
Issue :
48
Database :
MEDLINE
Journal :
Angewandte Chemie (International ed. in English)
Publication Type :
Academic Journal
Accession number :
30290053
Full Text :
https://doi.org/10.1002/anie.201810559