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[Transport and Toxicity of Cadmium].
- Source :
-
Nihon eiseigaku zasshi. Japanese journal of hygiene [Nihon Eiseigaku Zasshi] 2018; Vol. 73 (3), pp. 269-274. - Publication Year :
- 2018
-
Abstract
- Cadmium is a nonessential heavy metal and an industrial and environmental pollutant. It has been known that cadmium must enter cells to cause damage. To understand the transport systems responsible for cadmium entry into cells, it is important to determine the precise mechanisms underlying cadmium toxicity. Numerous studies have sought to unravel the exact pathways by which cadmium enters various cells and the mechanisms by which it causes toxicity in the organs of human and animals. The purpose of this review is to present the progress made regarding the mechanisms of cadmium transport in various cells and the mechanisms underlying cadmium toxicity in organs.
- Subjects :
- Animals
Apoptosis
Biological Transport
Calcium Channels physiology
Carrier Proteins physiology
Cells metabolism
Endoplasmic Reticulum Stress physiology
Humans
Metallothionein physiology
Mice
Repressor Proteins physiology
Transcription Factors physiology
Cadmium metabolism
Cadmium toxicity
Environmental Pollutants metabolism
Environmental Pollutants toxicity
Subjects
Details
- Language :
- Japanese
- ISSN :
- 1882-6482
- Volume :
- 73
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Nihon eiseigaku zasshi. Japanese journal of hygiene
- Publication Type :
- Academic Journal
- Accession number :
- 30270291
- Full Text :
- https://doi.org/10.1265/jjh.73.269