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Interferon-α enhances the IL-12-induced STAT4 activation selectively in carriers of the STAT4 SLE risk allele rs7574865[T].
- Source :
-
Annals of the rheumatic diseases [Ann Rheum Dis] 2019 Mar; Vol. 78 (3), pp. 429-431. Date of Electronic Publication: 2018 Sep 29. - Publication Year :
- 2019
-
Abstract
- Competing Interests: Competing interests: None declared.
- Subjects :
- Adult
Alleles
CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Female
Genetic Predisposition to Disease
Humans
Phosphorylation genetics
Polymorphism, Single Nucleotide
Interferon-alpha physiology
Interleukin-12 physiology
Lupus Erythematosus, Systemic genetics
STAT4 Transcription Factor genetics
Transcriptional Activation genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1468-2060
- Volume :
- 78
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Annals of the rheumatic diseases
- Publication Type :
- Report
- Accession number :
- 30269051
- Full Text :
- https://doi.org/10.1136/annrheumdis-2018-213836