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Nuts and Bolts of Fecal Microbiota Transplantation.

Authors :
Krajicek E
Fischer M
Allegretti JR
Kelly CR
Source :
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2019 Jan; Vol. 17 (2), pp. 345-352. Date of Electronic Publication: 2018 Sep 27.
Publication Year :
2019

Abstract

Clostridium difficile infection (CDI) has become the leading cause of nosocomial infection in the United States with significant risk of both morbidity and mortality. While antimicrobial therapy forms the basis of treatment, there are several clinical scenarios in which antimicrobial therapy alone is insufficient. Evidence continues to show the safety and efficacy fecal microbiota transplantation (FMT) in recurrent and severe CDI. This review will outline FMT efficacy, safety, and indications and present practical advice for clinicians interested in best practices around delivery of FMT.<br /> (Copyright © 2019 AGA Institute. Published by Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1542-7714
Volume :
17
Issue :
2
Database :
MEDLINE
Journal :
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Publication Type :
Academic Journal
Accession number :
30268564
Full Text :
https://doi.org/10.1016/j.cgh.2018.09.029