Defining antimicrobial resistance in cystic fibrosis.

Authors :: Kidd TJ
Canton R
Ekkelenkamp M
Johansen HK
Gilligan P
LiPuma JJ
Bell SC
Elborn JS
Flume PA
VanDevanter DR
Waters VJ
Source :: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2018 Nov; Vol. 17 (6), pp. 696-704. Date of Electronic Publication: 2018 Sep 25.
Publication Year :: 2018
Abstract: Antimicrobial resistance (AMR) can present significant challenges in the treatment of cystic fibrosis (CF) lung infections. In CF and other chronic diseases, AMR has a different profile and clinical consequences compared to acute infections and this requires different diagnostic and treatment approaches. This review defines AMR, explains how it occurs, describes the methods used to measure AMR as well as their limitations, and concludes with future directions for research and development in the area of AMR in CF.<br /> (Copyright © 2018 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.)

Subjects :: Humans
Microbiological Techniques methods
Anti-Bacterial Agents pharmacology
Cystic Fibrosis microbiology
Cystic Fibrosis therapy
Drug Resistance, Bacterial drug effects
Drug Resistance, Bacterial physiology

Language :: English
ISSN :: 1873-5010
Volume :: 17
Issue :: 6
Database :: MEDLINE
Journal :: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Publication Type :: Academic Journal
Accession number :: 30266518
Full Text :: https://doi.org/10.1016/j.jcf.2018.08.014