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Hearing Impairment and Type 1 Diabetes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Cohort.
- Source :
-
Diabetes care [Diabetes Care] 2018 Dec; Vol. 41 (12), pp. 2495-2501. Date of Electronic Publication: 2018 Sep 25. - Publication Year :
- 2018
-
Abstract
- Objective: To evaluate the prevalence of hearing impairment in participants with type 1 diabetes enrolled in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study and compare with that of a spousal control group without diabetes. Among participants with type 1 diabetes, to evaluate the association of hearing impairment with prior DCCT therapy and overall glycemia.<br />Research Design and Methods: DCCT/EDIC participants ( n = 1,150) and 288 spouses without diabetes were recruited for the DCCT/EDIC Hearing Study. All subjects completed a self-administered questionnaire, medical history, and physical measurements. Audiometry was performed by study-certified personnel; audiograms were assessed centrally. Speech-frequency (pure-tone average [PTA] thresholds at 500, 1,000, 2,000, and 4,000 Hz) and high-frequency impairment (PTA thresholds at 3,000, 4,000, 6,000, and 8,000 Hz) were defined as PTA >25 dB hearing loss. Logistic regression models were adjusted for age and sex.<br />Results: DCCT/EDIC participants and spousal control subjects were similar in age, race, education, smoking, and systolic blood pressure. There were no statistically significant differences between groups in the prevalence or adjusted odds of speech- or high-frequency impairment in either ear. Among participants with type 1 diabetes, for every 10% increase in the time-weighted mean HbA <subscript>1c</subscript> , there was a 32% (95% CI 1.15-1.50) and 19% (95% CI 1.07-1.33) increase in speech- and high-frequency hearing impairment, respectively.<br />Conclusions: We found no significant difference in the prevalence of hearing impairment between the group with type 1 diabetes and the spousal control group. Among those with type 1 diabetes, higher mean HbA <subscript>1c</subscript> over time was associated with hearing impairment.<br /> (© 2018 by the American Diabetes Association.)
- Subjects :
- Aged
Blood Glucose metabolism
Cohort Studies
Diabetes Complications complications
Diabetes Mellitus, Type 1 blood
Diabetes Mellitus, Type 1 complications
Female
Hearing Loss complications
Humans
Male
Middle Aged
Prevalence
Risk Factors
Surveys and Questionnaires
United States epidemiology
Diabetes Complications epidemiology
Diabetes Mellitus, Type 1 epidemiology
Hearing Loss epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1935-5548
- Volume :
- 41
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Diabetes care
- Publication Type :
- Academic Journal
- Accession number :
- 30254082
- Full Text :
- https://doi.org/10.2337/dc18-0625