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Allergic reactions to atropine eye drops for retardation of progressive myopia in children.
- Source :
-
Indian journal of ophthalmology [Indian J Ophthalmol] 2018 Oct; Vol. 66 (10), pp. 1446-1450. - Publication Year :
- 2018
-
Abstract
- Purpose: To report clinical manifestations of ocular allergy to atropine eye drops used for retardation of progressive myopia in children.<br />Methods: Myopic children, who developed bothersome itching that subsided promptly after cessation of atropine eye drops, were included. History of systemic or ocular allergy, preexisting ocular conditions, and clinical features of allergy were noted.<br />Results: Six children, age 5-15 years, were included. Four developed allergy to 1% atropine sulfate eye drops and two to 0.01% concentration of atropine sulfate. The onset of allergy was within a month to as late as 4 years after using atropine eye drops. The severity of allergy was higher with 1% concentration. The most common symptoms of atropine allergy were itching and burning. The most common signs were lid swelling and hyperemia. The allergic manifestations promptly reversed with the stoppage of eye drops. Reintroduction was possible in three patients, either by reducing the concentration of atropine or using benzalkonium free formulation.<br />Conclusion: Allergy to atropine eye drops in children may develop within a few weeks or after many years of usage. Prompt cessation followed by a reintroduction and continuation of therapy may be possible in few patients.<br />Competing Interests: There are no conflicts of interest
- Subjects :
- Adolescent
Atropine administration & dosage
Child
Child, Preschool
Dermatitis, Allergic Contact etiology
Drug Hypersensitivity complications
Female
Humans
Male
Mydriatics administration & dosage
Mydriatics adverse effects
Myopia, Degenerative physiopathology
Ophthalmic Solutions
Atropine adverse effects
Dermatitis, Allergic Contact diagnosis
Drug Hypersensitivity diagnosis
Myopia, Degenerative drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1998-3689
- Volume :
- 66
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Indian journal of ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 30249831
- Full Text :
- https://doi.org/10.4103/ijo.IJO_165_18