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Whipple's disease: case report and review of the literature.
- Source :
-
Journal of gastrointestinal and liver diseases : JGLD [J Gastrointestin Liver Dis] 2018 Sep; Vol. 27 (3), pp. 331-336. - Publication Year :
- 2018
-
Abstract
- Whipple's disease (WD) is known as an infrequent, systemic, chronic infection caused by the actinomycete Tropherima whipplei (T. whipplei). The disease is frequently characterized by a long prodromal and protean extra-intestinal phase, which often causes misdiagnosis and inappropriate treatments. Herein, we describe the case a 62-year-old man with a histological diagnosis of WD established when oral steroid treatment was started due to rheumatic manifestations, triggering intestinal symptoms. Systematic review of the literature was performed to include studies where WD was eventually diagnosed on duodenal biopsies. Three patients' subgroups were identified according to the clinical presentation.
- Subjects :
- Anti-Bacterial Agents therapeutic use
Biopsy
Duodenoscopy
Duodenum pathology
Humans
Intestinal Mucosa pathology
Middle Aged
Tropheryma drug effects
Whipple Disease diagnosis
Whipple Disease drug therapy
Duodenum microbiology
Intestinal Mucosa microbiology
Tropheryma isolation & purification
Whipple Disease microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1842-1121
- Volume :
- 27
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of gastrointestinal and liver diseases : JGLD
- Publication Type :
- Academic Journal
- Accession number :
- 30240479
- Full Text :
- https://doi.org/10.15403/jgld.2014.1121.273.fra