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Biomimetic synthesis of the bisindole framework present in sciodole, an alkaloid from Tricholoma sciodes.

Authors :
Homer JA
Sperry J
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2018 Oct 03; Vol. 16 (38), pp. 6882-6885.
Publication Year :
2018

Abstract

A synthesis of the unique bisindole framework present in the mushroom-derived alkaloid sciodole has been achieved, validating a biosynthesis proposal that the C-N bisindole bond present in the natural product is forged by amination of an azafulvenium.

Details

Language :
English
ISSN :
1477-0539
Volume :
16
Issue :
38
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
30229791
Full Text :
https://doi.org/10.1039/c8ob02142b