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[Nucleotide sequences in DNA showing preferential binding with distamycin A and acridine derivatives].

Authors :
Iashina LN
Ponomareva TA
Rechkunova NI
Zinov'ev VV
Malygin EG
Source :
Bioorganicheskaia khimiia [Bioorg Khim] 1986 Jun; Vol. 12 (6), pp. 764-70.
Publication Year :
1986

Abstract

The specificity of DNA X dye binding was studied. Antibiotic distamycin A was bound most strongly to the DNA sequences composed of three or more neighboring A X T pairs. Acrichin and 7-aminoacrichin proved to be weak specific inhibitors binding predominantly within the A X T regions.

Details

Language :
Russian
ISSN :
0132-3423
Volume :
12
Issue :
6
Database :
MEDLINE
Journal :
Bioorganicheskaia khimiia
Publication Type :
Academic Journal
Accession number :
3022753