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Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden.
- Source :
-
Emerging infectious diseases [Emerg Infect Dis] 2018 Oct; Vol. 24 (10), pp. 1874-1881. - Publication Year :
- 2018
-
Abstract
- By collecting and analyzing diapers, we identified a >6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae for healthy preschool children in Sweden (p<0.0001). For 6 of the 50 participating preschools, the carriage rate was >40%. We analyzed samples from 334 children and found 56 containing >1 ESBL producer. The prevalence in the study population increased from 2.6% in 2010 to 16.8% in 2016 (p<0.0001), and for 6 of the 50 participating preschools, the carriage rate was >40%. Furthermore, 58% of the ESBL producers were multidrug resistant, and transmission of ESBL-producing and non-ESBL-producing strains was observed at several of the preschools. Toddlers appear to be major carriers of ESBL producers in Sweden.
- Subjects :
- Anti-Bacterial Agents pharmacology
Child, Preschool
Enterobacteriaceae Infections transmission
Female
Follow-Up Studies
Genome, Bacterial
Humans
Infant
Male
Microbial Sensitivity Tests
Population Surveillance
Prevalence
Sweden epidemiology
beta-Lactamases genetics
Carrier State
Enterobacteriaceae classification
Enterobacteriaceae drug effects
Enterobacteriaceae genetics
Enterobacteriaceae metabolism
Enterobacteriaceae Infections epidemiology
Enterobacteriaceae Infections microbiology
beta-Lactamases metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1080-6059
- Volume :
- 24
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Emerging infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 30226162
- Full Text :
- https://doi.org/10.3201/eid2410.171842