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Chemical Constituents from Croton Species and Their Biological Activities.
- Source :
-
Molecules (Basel, Switzerland) [Molecules] 2018 Sep 12; Vol. 23 (9). Date of Electronic Publication: 2018 Sep 12. - Publication Year :
- 2018
-
Abstract
- The genus Croton belongs to the Euphorbiaceae family, which comprises approximately 1300 species. Many Croton species have been used as folk medicines. This review focuses on the chemical constituents from Croton species and their relevant biological activities, covering the period from 2006 to 2018. A total of 399 new compounds, including 339 diterpenoids, were reported. Diterpenoids are characteristic components of the Croton species. These isolated compounds exhibited a broad spectrum of bioactivities, including cytotoxic, anti-inflammatory, antifungal, acetylcholinesterase inhibitory, and neurite outgrowth-promoting properties. The present review provides a significant clue for further research of the chemical constituents from the Croton species as potential medicines.
- Subjects :
- Animals
Anti-Inflammatory Agents chemistry
Anti-Inflammatory Agents pharmacology
Antifungal Agents chemistry
Antifungal Agents pharmacology
Antioxidants chemistry
Antioxidants pharmacology
Cholinesterase Inhibitors chemistry
Cholinesterase Inhibitors pharmacology
Humans
Medicine, Traditional
Molecular Structure
Plant Extracts chemistry
Plant Extracts pharmacology
Croton chemistry
Diterpenes chemistry
Diterpenes pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1420-3049
- Volume :
- 23
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Molecules (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 30213129
- Full Text :
- https://doi.org/10.3390/molecules23092333