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Acrophobia in a Young Girl with Parathyroid Hormone Resistance (Pseudohypoparathyroidism).
- Source :
-
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2018 Sep; Vol. 28 (9), pp. S166-S168. - Publication Year :
- 2018
-
Abstract
- Pseudohypoparathyroidism (PHP) is an extremely rare group of disorders. It is a spectrum of disorders caused by end organ resistance to parathyroid hormone (PTH) and is represented by impaired signalling that activates cAMP dependent pathways via alpha subunit of G-protein (GS). It is characterised by hypocalcemia, hyperphosphatemia, raised PTH levels due to insensitivity to biological activity of PTH, and normal renal function tests. We describe a case of 10-year girl who presented with fear of falling down from heights. Her laboratory evaluation and skeletal survey showed evidence of PHP along with features of Albright's hereditary osteodystrophy (AHO) pointing towards the diagnosis of PHP type 1a.
Details
- Language :
- English
- ISSN :
- 1681-7168
- Volume :
- 28
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
- Publication Type :
- Academic Journal
- Accession number :
- 30173686
- Full Text :
- https://doi.org/10.29271/jcpsp.2018.09.S166