Depression and psychosis in ADCY5-related dyskinesia-part of the phenotypic spectrum?

Authors :: Vijiaratnam N
Newby R
Kempster PA
Source :: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2018 Nov; Vol. 57, pp. 167-168. Date of Electronic Publication: 2018 Aug 30.
Publication Year :: 2018
Abstract: This report details prominent neuropsychiatric features in one family with an ADCY5 gene mutation. ADCY5 mutations cause a variable motor phenotype, though most cases have some core involuntary movement features. The psychiatric aspects of the disorder have not been emphasised in previous publications. We discuss possible pathogenesis.<br /> (Copyright © 2018 Elsevier Ltd. All rights reserved.)

Subjects :: Adult
Depression complications
Depression genetics
Dyskinesias complications
Dyskinesias genetics
Humans
Male
Mutation
Psychotic Disorders complications
Psychotic Disorders genetics
Adenylyl Cyclases genetics
Depression diagnosis
Dyskinesias diagnosis
Phenotype
Psychotic Disorders diagnosis

Language :: English
ISSN :: 1532-2653
Volume :: 57
Database :: MEDLINE
Journal :: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Publication Type :: Academic Journal
Accession number :: 30172639
Full Text :: https://doi.org/10.1016/j.jocn.2018.08.049

Full Text Access

Tools