Back to Search
Start Over
Long-term outcomes of total ureterectomy with ileal-ureteral substitution treatment for ureteral cancer: a single-center experience.
- Source :
-
BMC urology [BMC Urol] 2018 Aug 31; Vol. 18 (1), pp. 73. Date of Electronic Publication: 2018 Aug 31. - Publication Year :
- 2018
-
Abstract
- Background: To explore the feasibility and long-term outcomes of renal preservation in a retrospective cohort of patients with ureteral urothelial carcinoma undergoing total ureterectomy with ileal-ureteral substitution.<br />Methods: A retrospective review of the data from patients treated with total ureterectomy with ileal-ureteral substitution from 1988 to 2016 was performed. The pre-operative oncological status, long-term oncological outcome, long-term renal functional outcome, early and late complications were analyzed.<br />Results: A total of eight patients with a median age of 70 years were included. The median follow-up time was 109 months. Six patients had multi-focal tumor involvement over the target ureter, and six patients had bilateral upper tract involvement. Only one patient encountered the upper-tract recurrence. The 2 and 5-year cancer-specific survival rates were 87.5 and 75.0%, respectively. The renal function was well-preserved in most patients, with only one patient needed life-long postoperative hemodialysis. Five patients experienced early complications and four patients experienced late complications. No perioperative mortality happened.<br />Conclusions: A total ureterectomy with an ileal-ureteral substitution is feasible for treating ureteral urothelial carcinoma when a renal-sparing procedure is indicated. It provides good long-term oncological outcomes over the upper tract, and it also preserves the renal function.
- Subjects :
- Adult
Aged
Female
Follow-Up Studies
Humans
Kidney physiology
Male
Middle Aged
Neoplasm Recurrence, Local
Postoperative Complications
Retrospective Studies
Survival Rate
Treatment Outcome
Ureteral Neoplasms mortality
Urinary Bladder Neoplasms
Urologic Surgical Procedures methods
Ileum transplantation
Ureter surgery
Ureteral Neoplasms surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1471-2490
- Volume :
- 18
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMC urology
- Publication Type :
- Academic Journal
- Accession number :
- 30170590
- Full Text :
- https://doi.org/10.1186/s12894-018-0389-5