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A case of ovarian clear cell carcinoma arising from ovarian mature cystic teratoma.
- Source :
-
Journal of ovarian research [J Ovarian Res] 2018 Aug 30; Vol. 11 (1), pp. 74. Date of Electronic Publication: 2018 Aug 30. - Publication Year :
- 2018
-
Abstract
- Background: It is well known that ovarian mature cystic teratomas (MCTs) occasionally go through malignant transformations. Among these, approximately 75% of histological types are squamous cell carcinoma, with the other types being exceptionally rare. We report an extremely rare case of ovarian clear cell carcinoma arising from ovarian mature cystic teratoma.<br />Case Presentation: The case was a 71-year-old woman with abdominal distention. Ultrasonography and magnetic resonance imaging showed a huge mass in her abdominal cavity. Fluorodeoxyglucose-positron emission tomography (FDG-PET) showed FDG uptake not only in the pelvic tumor but also in the hepatic nodule, thus suggesting metastases. We performed a total abdominal hysterectomy, bilateral salpingo-oophorectomy, and an omentectomy. The pathological diagnosis showed clear cell carcinoma of the right ovary which arose from the MCT with malignant transformation pT2aNXM1. Although the patient underwent chemotherapy, she died after 17 months.<br />Conclusion: This case is histologically characteristic of the proof of transition from simple squamous epithelium via simple glandular epithelium to papillary change with atypia. This is the first case report of unaccompanied clear cell carcinoma arising from MCT reported in English literatures.
- Subjects :
- Aged
Female
Humans
Hysterectomy
Magnetic Resonance Imaging
Ovarian Neoplasms diagnostic imaging
Ovarian Neoplasms drug therapy
Ovarian Neoplasms surgery
Ovary diagnostic imaging
Ovary pathology
Ovary surgery
Positron-Emission Tomography
Teratoma diagnostic imaging
Teratoma drug therapy
Teratoma surgery
Tomography, X-Ray Computed
Ovarian Neoplasms pathology
Teratoma pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1757-2215
- Volume :
- 11
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of ovarian research
- Publication Type :
- Academic Journal
- Accession number :
- 30165878
- Full Text :
- https://doi.org/10.1186/s13048-018-0446-4