Probing Dynamic Library of Metal-Oxo Building Blocks with γ-Cyclodextrin.

Authors :: Falaise C
Moussawi MA
Floquet S
Abramov PA
Sokolov MN
Haouas M
Cadot E
Source :: Journal of the American Chemical Society [J Am Chem Soc] 2018 Sep 12; Vol. 140 (36), pp. 11198-11201. Date of Electronic Publication: 2018 Sep 04.
Publication Year :: 2018
Abstract: Formation of one of the most representative polyoxometalate (POM) archetypes, namely the Lindqvist anion M <subscript>6</subscript> O <subscript>19</subscript> <superscript>2-</superscript> with M = Mo <superscript>VI</superscript> or W <superscript>VI</superscript> , was considered as elusive in aqueous solution. Herein, we report on the host-guest stabilization of the M <subscript>6</subscript> O <subscript>19</subscript> <superscript>2-</superscript> species with M = Mo or W from aqueous solution using γ-cyclodextrin as trapping agent. The adduct {M <subscript>6</subscript> O <subscript>19</subscript> @γ-CD} <superscript>2-</superscript> reveals remarkable hydrolytic stability that offers new opportunities for exploring potentialities of molybdates or tungstates in the field of biology and medicine, when combined to CDs as efficient drug carrier/delivery agents.