Back to Search
Start Over
Clinical impact of routine angiographic follow-up after percutaneous coronary interventions on unprotected left main.
- Source :
-
Cardiology journal [Cardiol J] 2018; Vol. 25 (5), pp. 582-588. Date of Electronic Publication: 2018 Aug 29. - Publication Year :
- 2018
-
Abstract
- Background: Patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stent (DES) on unprotected left main (ULM) represent a complex subset. The role of routine coronary angiography at follow up in this subset remains debated.<br />Methods: At the documented center, all patients undergoing successful PCI on ULM lesions performing angiographic follow-up is suggested, but adherence to such a recommendation is inhomogeneous. Consecutive patients undergoing DES PCI on ULM were enrolled and experienced no adverse events during the first 6 months. Patients were then allocated to two groups: those undergoing routine control angiography (CA) and those undergoing clinical follow-up (CF). Primary endpoint was major adverse cardiac events (MACE) defined as cardiac death, myocardial infarction and urgent repeat target vessel revascularization.<br />Results: A total of 190 patients underwent successful DES implantation on ULM and the study population was without early events. CA was performed at 6 months after the index procedure in 91 (48%) patients. After 35 ± 21 months, MACE rates were significantly more common in the CF group as compared with the CA group (16.2% vs. 4.3%, p = 0.009). At multivariable analysis, CA was associated with reduced MACE risk (HR 0.13, 95% CI 0.1-0.7, p = 0.028). Of note, this was mainly driven by higher cardiac death rate in those undergoing CF than in those undergoing CA (p = 0.01).<br />Conclusions: CA after complex PCI, such as ULM PCI, is associated with reduced MACE. Such an observation calls for appropriately designed randomized trials.
- Subjects :
- Aged
Coronary Artery Disease surgery
Coronary Vessels surgery
Drug-Eluting Stents
Female
Follow-Up Studies
Heart Arrest epidemiology
Heart Arrest etiology
Humans
Incidence
Italy epidemiology
Male
Myocardial Infarction diagnosis
Myocardial Infarction epidemiology
Myocardial Infarction etiology
Postoperative Complications etiology
Prognosis
Reproducibility of Results
Survival Rate trends
Time Factors
Coronary Angiography methods
Coronary Artery Disease diagnosis
Coronary Vessels diagnostic imaging
Percutaneous Coronary Intervention adverse effects
Postoperative Complications epidemiology
Registries
Subjects
Details
- Language :
- English
- ISSN :
- 1898-018X
- Volume :
- 25
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cardiology journal
- Publication Type :
- Academic Journal
- Accession number :
- 30155864
- Full Text :
- https://doi.org/10.5603/CJ.a2018.0092