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New Naphthalene Derivatives from the Bulbs of Eleutherine americana with Their Protective Effect on the Injury of HUVECs.
- Source :
-
Molecules (Basel, Switzerland) [Molecules] 2018 Aug 22; Vol. 23 (9). Date of Electronic Publication: 2018 Aug 22. - Publication Year :
- 2018
-
Abstract
- Five new naphthalene derivatives, named Eleutherols A⁻C ( 1 ⁻ 3 ) and Eleuthinones B⁻C ( 4 , 5 ), together with three known compounds were isolated from the bulbs of Eleutherine americana . Their structures were elucidated on the basis of spectroscopic analysis including HR-ESI-MS, 1D and 2D NMR techniques. These compounds exhibited a potent effect against the injury of human umbilical vein endothelial cell (HUVECs) induced by high concentrations of glucose in vitro.
- Subjects :
- Endothelial Cells metabolism
Human Umbilical Vein Endothelial Cells
Humans
Magnetic Resonance Spectroscopy
Molecular Structure
Protective Agents pharmacology
Spectrometry, Mass, Electrospray Ionization
Endothelial Cells drug effects
Naphthalenes chemistry
Naphthalenes pharmacology
Plant Extracts chemistry
Plant Extracts pharmacology
Plant Roots chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1420-3049
- Volume :
- 23
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Molecules (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 30135380
- Full Text :
- https://doi.org/10.3390/molecules23092111