Back to Search
Start Over
Bioavailability of Vitamin B 12 from Dairy Products Using a Pig Model.
- Source :
-
Nutrients [Nutrients] 2018 Aug 21; Vol. 10 (9). Date of Electronic Publication: 2018 Aug 21. - Publication Year :
- 2018
-
Abstract
- The present study compares the bioavailability of vitamin B <subscript>12</subscript> (B <subscript>12</subscript> ) of dairy products or synthetic B <subscript>12</subscript> , using the pig as an experimental model for humans. Eleven pigs were used in a cross-over design to assess the net portal drained viscera (PDV) flux of blood plasma B <subscript>12</subscript> after ingestion of tofu (TF; devoid of B <subscript>12</subscript> ), Swiss cheese (SC), Cheddar cheese (CC), yogurt (YG), and synthetic B <subscript>12</subscript> (TB <subscript>12</subscript> ; TF supplemented with cyanocobalamin), providing a total of 25 µg of B <subscript>12</subscript> each. PDV blood plasma flow for SC and CC were higher than for TF and TB <subscript>12</subscript> ( p ≤ 0.04) whereas YG was higher than TF ( p = 0.05). Porto-arterial difference of blood plasma B <subscript>12</subscript> concentrations were higher for CC and TB <subscript>12</subscript> than for TF and YG ( p ≤ 0.04) but not different from SC ( p ≥ 0.15). Net PDV flux of B <subscript>12</subscript> was only different from zero for CC. However, the net PDV flux of B <subscript>12</subscript> for CC was not different from SC or TB <subscript>12</subscript> . Cumulative net PDV flux of B <subscript>12</subscript> for SC, TB <subscript>12</subscript> , and CC were 2.9, 4.4, and 8.3 µg 23 h post-meal, corresponding to a bioavailability of 11.6%, 17.5%, and 33.0%, respectively. In conclusion, CC had the best bioavailability of B <subscript>12</subscript> among the tested dairy products or compared to synthetic B <subscript>12</subscript> .
Details
- Language :
- English
- ISSN :
- 2072-6643
- Volume :
- 10
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Nutrients
- Publication Type :
- Academic Journal
- Accession number :
- 30134590
- Full Text :
- https://doi.org/10.3390/nu10091134