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Low doses of triazine xenobiotics mobilize ABA and cytokinin regulations in a stress- and low-energy-dependent manner.
- Source :
-
Plant science : an international journal of experimental plant biology [Plant Sci] 2018 Sep; Vol. 274, pp. 8-22. Date of Electronic Publication: 2018 May 01. - Publication Year :
- 2018
-
Abstract
- The extent of residual contaminations of pesticides through drift, run-off and leaching is a potential threat to non-target plant communities. Arabidopsis thaliana responds to low doses of the herbicide atrazine, and of its degradation products, desethylatrazine and hydroxyatrazine, not only in the long term, but also under conditions of short-term exposure. In order to investigate underlying molecular mechanisms of low-dose responses and to decipher commonalities and specificities between different chemical treatments, parallel transcriptomic studies of the early effects of the atrazine-desethylatrazine-hydroxyatrazine chemical series were undertaken using whole-genome microarrays. All of the triazines under study produced coordinated and specific changes in gene expression. Hydroxyatrazine-responsive genes were mainly linked to root development, whereas atrazine and desethylatrazine mostly affected molecular signaling networks implicated in stress and hormone responses. Analysis of signaling-related genes, promoter sites and shared-function interaction networks highlighted the involvement of energy-, stress-, abscisic acid- and cytokinin-regulated processes, and emphasized the importance of cold-, heat- and drought-related signaling in the perception of low doses of triazines. These links between low-dose xenobiotic impacts and stress-hormone crosstalk pathways give novel insights into plant-pesticide interactions and plant-pollution interactions that are essential for toxicity evaluation in the context of environmental risk assessment.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)
- Subjects :
- Arabidopsis drug effects
Arabidopsis metabolism
Atrazine pharmacology
Energy Metabolism drug effects
Gene Expression Regulation, Plant drug effects
Oligonucleotide Array Sequence Analysis
Polymerase Chain Reaction
Stress, Physiological drug effects
Abscisic Acid metabolism
Cytokinins metabolism
Triazines pharmacology
Xenobiotics pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-2259
- Volume :
- 274
- Database :
- MEDLINE
- Journal :
- Plant science : an international journal of experimental plant biology
- Publication Type :
- Academic Journal
- Accession number :
- 30080643
- Full Text :
- https://doi.org/10.1016/j.plantsci.2018.04.025