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Eyelid Dermatitis and Contact Sensitization to Nickel: Results from an Italian Multi-Centric Observational Study.
- Source :
-
Endocrine, metabolic & immune disorders drug targets [Endocr Metab Immune Disord Drug Targets] 2019; Vol. 19 (1), pp. 38-45. - Publication Year :
- 2019
-
Abstract
- Background: Due to the sensitizing constituents of eye cosmetics, allergic contact dermatitis is considered a frequent cause of eyelid dermatitis. An association between eyelid dermatitis and nickel contained in make-ups remains controversial.<br />Objective: The study aimed to assess the association between nickel allergy, the use of pigmented makeup products and self-reported eyelid dermatitis.<br />Method: This multi-centric, cross-sectional study enrolled 165 women sensitized to nickel (patients) and 103 women without intolerance to metals (controls). We recorded: demographics, atopy, use of pigmented eye cosmetics (mascara, eyeshadow, eyeliner, eyebrow pencil), and previous eyelid dermatitis. Among the patients, any co-sensitization to cosmetics or metals was recorded.<br />Results: 87.3% of the patients and 91.3% of the controls reported their use of eye make-up; 44.9% and 52.4%, respectively, reported previous episodes of eyelid dermatitis, without significant differences. The occurrence of eyelid dermatitis was significantly associated with the use of eye make-up products, both in general and considering each product separately. Age, atopy, or co-sensitization to other metals or cosmetics did not affect the occurrence of eyelid dermatitis.<br />Conclusion: Nickel allergy should not be considered the main risk factor for eyelid dermatitis. The use of pigmented eye make-up may be a triggering factor for eyelid dermatitis, probably due to an irritant action.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
- Subjects :
- Adolescent
Adult
Aged
Allergens analysis
Cosmetics analysis
Cross-Sectional Studies
Female
Humans
Incidence
Italy epidemiology
Middle Aged
Young Adult
Cosmetics adverse effects
Dermatitis, Allergic Contact epidemiology
Dermatitis, Allergic Contact etiology
Eyelid Diseases epidemiology
Eyelid Diseases etiology
Nickel adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 2212-3873
- Volume :
- 19
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Endocrine, metabolic & immune disorders drug targets
- Publication Type :
- Academic Journal
- Accession number :
- 30062976
- Full Text :
- https://doi.org/10.2174/1871530318666180731114418