Back to Search
Start Over
Point-of-Care Periodontitis Testing: Biomarkers, Current Technologies, and Perspectives.
- Source :
-
Trends in biotechnology [Trends Biotechnol] 2018 Nov; Vol. 36 (11), pp. 1127-1144. Date of Electronic Publication: 2018 Jul 02. - Publication Year :
- 2018
-
Abstract
- Periodontitis has become one of the most universal chronic inflammatory diseases worldwide. Subclinical symptom progression, ultimately leading to permanent damage, calls for early diagnosis and long-term monitoring. However, traditional clinical diagnostic methods are complex and expensive, and cannot meet these requirements. Recently, with more biomarkers and the development of new technologies, various point-of-care testing (POCT) platforms have been developed for periodontitis diagnosis and monitoring. These are easy to perform, rapid, low-cost, and are perfectly suited for high-frequency diagnosis of periodontitis at the point-of-care (POC). We summarize existing biomarkers of different periodontitis stages and recent developed POCT platforms (including lab-on-a-chip, paper-based platforms, and chairside tests), discuss their existing challenges and future potential, and provide some inspiration and guidelines for future POC periodontitis testing.<br /> (Copyright © 2018 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1879-3096
- Volume :
- 36
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Trends in biotechnology
- Publication Type :
- Academic Journal
- Accession number :
- 30041883
- Full Text :
- https://doi.org/10.1016/j.tibtech.2018.05.013