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Therapeutic applications of cannabinoids.
- Source :
-
Chemico-biological interactions [Chem Biol Interact] 2018 Sep 25; Vol. 293, pp. 77-88. Date of Electronic Publication: 2018 Jul 21. - Publication Year :
- 2018
-
Abstract
- The psychoactive property of cannabinoids is well known and there has been a continuous controversy regarding the usage of these compounds for therapeutic purposes all over the world. Their use for medical and research purposes are restricted in various countries. However, their utility as medications should not be overshadowed by its negative physiological activities. This review article is focused on the therapeutic potential and applications of phytocannabinoids and endocannabinoids. We further highlights their mode of action, overall effects on physiology, various in vitro and in vivo studies that have been done so far and the extent to which these compounds can be useful in different disease conditions such as cancer, Alzheimer's disease, multiple sclerosis, pain, inflammation, glaucoma and many others. Thus, this work is an attempt to make the readers understand the positive implications of these compounds and indicates the significant developments of utilizing cannabinoids as therapeutic agents.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)
- Subjects :
- Cannabinoids adverse effects
Cannabinoids chemistry
Cardiomyopathies drug therapy
Cardiomyopathies pathology
Cardiovascular Diseases etiology
Central Nervous System Diseases drug therapy
Central Nervous System Diseases pathology
Endocannabinoids chemistry
Endocannabinoids therapeutic use
Eye Diseases drug therapy
Eye Diseases pathology
Humans
Neoplasms pathology
Pain drug therapy
Pain pathology
Receptors, Cannabinoid chemistry
Receptors, Cannabinoid metabolism
Cannabinoids therapeutic use
Neoplasms drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1872-7786
- Volume :
- 293
- Database :
- MEDLINE
- Journal :
- Chemico-biological interactions
- Publication Type :
- Academic Journal
- Accession number :
- 30040916
- Full Text :
- https://doi.org/10.1016/j.cbi.2018.07.018