Back to Search Start Over

Molecular targeted therapy: Treating cancer with specificity.

Authors :
Lee YT
Tan YJ
Oon CE
Source :
European journal of pharmacology [Eur J Pharmacol] 2018 Sep 05; Vol. 834, pp. 188-196. Date of Electronic Publication: 2018 Jul 20.
Publication Year :
2018

Abstract

Molecular targeted therapies are revolutionized therapeutics which interfere with specific molecules to block cancer growth, progression, and metastasis. Many molecular targeted therapies approved by the Food and Drug Administration (FDA), have demonstrated remarkable clinical success in the treatment of a myriad of cancer types including breast, leukemia, colorectal, lung, and ovarian cancers. This review provides an update on the different types of molecular targeted therapies used in the treatment of cancer, focusing on the fundamentals of molecular targeted therapy, its mode of action in cancer treatment, as well as its advantages and limitations.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1879-0712
Volume :
834
Database :
MEDLINE
Journal :
European journal of pharmacology
Publication Type :
Academic Journal
Accession number :
30031797
Full Text :
https://doi.org/10.1016/j.ejphar.2018.07.034