Tracking carbapenemase-producing bacteria by molecular typing: Population diversity and sampling pitfall.

Authors :: Baranovsky S
Romano-Bertrand S
Dumont Y
Masnou A
Hammer F
Godreuil S
Parer S
Jumas-Bilak E
Source :: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2018 Nov; Vol. 65, pp. 104-106. Date of Electronic Publication: 2018 Jul 17.
Publication Year :: 2018
Abstract: While typing methods are increasingly refined, the sampling of bacteria to be typed in healthcare-associated infection context retains less attention. Through 2 emblematic cases of in-hospital transmission of extensively drug-resistant bacteria producing carbapenemases, we demonstrate the impact of colony sampling in typing results. Because of intra-population diversity, typing several colonies of same species and resistotype was needed to fully track the transmission among patients. Bacterial population studies could better decipher transmission routes of healthcare-associated bacteria, thereby improving outbreak control.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)

Subjects :: Bacteria enzymology
Bacterial Infections epidemiology
Bacterial Infections microbiology
Bacterial Proteins biosynthesis
Biodiversity
Cross Infection epidemiology
Cross Infection microbiology
Humans
beta-Lactamases biosynthesis
Bacteria classification
Bacteria genetics
Bacterial Proteins genetics
Genetic Variation
Genetics, Population
Multilocus Sequence Typing
beta-Lactamases genetics

Language :: English
ISSN :: 1567-7257
Volume :: 65
Database :: MEDLINE
Journal :: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Publication Type :: Academic Journal
Accession number :: 30030207
Full Text :: https://doi.org/10.1016/j.meegid.2018.07.020

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