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Effects of Field-Realistic Concentrations of Carbendazim on Survival and Physiology in Forager Honey Bees (Hymenoptera: Apidae).
- Source :
-
Journal of insect science (Online) [J Insect Sci] 2018 Jul 01; Vol. 18 (4). - Publication Year :
- 2018
-
Abstract
- Carbendazim is nowadays widely used to control fungus in various nectariferous crops. Little is known about how honey bees, Apis mellifera L. (Hymenoptera: Apidae), respond to carbendazim exposure. In this study, the effects of field-realistic concentrations of carbendazim (4.516, 0.4516, and 0.04516 ppm) on the survival, biomarker enzyme activity (AChE, GST, CarE, and P450), and four antimicrobial peptide gene expression (hymenoptaecin, defensin, apidaecin, and abaecin) in forager honey bees were evaluated. The forager bees were fed with the pesticides for 10 d. The results showed that the field-realistic concentrations of carbendazim did not affect survival; activities of AChE, GST, and CarE; and expression levels of defensin and abaecin in forager bees. However, 4.516, 0.4516, and 0.04516 ppm of carbendazim all significantly inhibited the expression of hymenoptaecin and apidaecin (P < 0.01), while P450 (7-ethoxycoumarin-O-deethylase) activity was downregulated by 4.516 ppm of carbendazim (P < 0.05). Our results indicate that the field-realistic concentrations of carbendazim may alter the immune response and P450-mediated detoxification of honey bees. Thus, carbendazim should be discreetly used on nectariferous crops during florescence.
- Subjects :
- Animals
Antimicrobial Cationic Peptides genetics
Antimicrobial Cationic Peptides metabolism
Bees genetics
Bees physiology
Biomarkers metabolism
Dose-Response Relationship, Drug
Insect Proteins genetics
Insect Proteins metabolism
Bees drug effects
Benzimidazoles adverse effects
Carbamates adverse effects
Fungicides, Industrial adverse effects
Gene Expression drug effects
Longevity drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1536-2442
- Volume :
- 18
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of insect science (Online)
- Publication Type :
- Academic Journal
- Accession number :
- 30010928
- Full Text :
- https://doi.org/10.1093/jisesa/iey069