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Use of a novel chitosan-based dressing on split-thickness skin graft donor sites: a pilot study.
- Source :
-
Journal of wound care [J Wound Care] 2018 Jul 01; Vol. 27 (Sup7), pp. S12-S18. - Publication Year :
- 2018
-
Abstract
- Objective: Split-thickness skin graft (STSG) donor site dressings can play an integral role in reducing donor site morbidity. This study tested a novel, chitosan-based wound dressing, Opticell Ag, as an STSG donor site dressing for wounds <10% total body surface area (TBSA).<br />Method: Between January and December 2016, the chitosan-based dressing was placed on participating patients' donor sites immediately following graft harvest and covered with a transparent occlusive dressing. Pain was evaluated on postoperative day one, before dressing change between days 5-7, and before and after dressing removal between days 10-14 using the Visual Analog Scale (VAS). The extent of re-epithelialisation was determined between day 10-14 and at one month, and healing quality was also evaluated at one month post-operatively using the Vancouver Scar Scale (VSS).<br />Results: A total of 19 patients were recruited, of which 16 completed the study. Patients experienced mild-to-moderate pain in their donor sites when the chitosan-based dressing was used. Pain decreased significantly between postoperative day one and days 10-14, as well as between days 5-7 and 10-14. The mean percentage of re-epithelialisation on days 10-14 was 92% and by one month was 99%. The mean VSS at one month was 3.2±1.4. There were no statistically significant differences between patients' re-epithelialisation rates or VSS scores. There were unplanned dressing changes in four patients. No donor site infections or other adverse events were identified.<br />Conclusion: The chitosan-based dressing tested in this study is safe, effective, and associated with reasonable pain control and acceptable healing quality. The results suggest that it is a promising STSG donor site dressing.
- Subjects :
- Adult
Aged
Cohort Studies
Female
Humans
Male
Middle Aged
Pilot Projects
Postoperative Care methods
Prognosis
Re-Epithelialization drug effects
Re-Epithelialization physiology
Skin Transplantation adverse effects
Time Factors
Treatment Outcome
Wound Healing drug effects
Chitosan therapeutic use
Occlusive Dressings
Skin Transplantation methods
Surgical Wound Infection prevention & control
Transplant Donor Site physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 0969-0700
- Volume :
- 27
- Issue :
- Sup7
- Database :
- MEDLINE
- Journal :
- Journal of wound care
- Publication Type :
- Academic Journal
- Accession number :
- 30008255
- Full Text :
- https://doi.org/10.12968/jowc.2018.27.Sup7.S12