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The structural gene for aldolase B (ALDB) maps to 9q13----32.
- Source :
-
Annals of human genetics [Ann Hum Genet] 1985 Jul; Vol. 49 (3), pp. 173-80. - Publication Year :
- 1985
-
Abstract
- We used a cloned cDNA probe for the B subunit of human aldolase (ALDB) and Southern blotting techniques to analyse DNA from a series of rodent X human somatic cell hybrids for the presence of specific ALDB-related sequences. Our results provide evidence for the assignment of the gene for ALDB to chromosome 9. Moreover, by direct gene dosage determination in two patients with chromosome 9 unbalanced rearrangements and by in situ hybridization we refined the regional chromosomal assignment to 9q13----q32 and most probably to 9q21.3----9q22.2.
Details
- Language :
- English
- ISSN :
- 0003-4800
- Volume :
- 49
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Annals of human genetics
- Publication Type :
- Academic Journal
- Accession number :
- 3000275
- Full Text :
- https://doi.org/10.1111/j.1469-1809.1985.tb01691.x