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A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients.
- Source :
-
Science (New York, N.Y.) [Science] 1985 Nov 15; Vol. 230 (4727), pp. 810-3. - Publication Year :
- 1985
-
Abstract
- A newly identified protein from HTLV-III/LAV, the virus implicated as the etiologic agent of the acquired immune deficiency syndrome, was studied. This protein, which has a molecular weight of 27,000 (p27), was shown by amino acid sequencing to have a coding origin 3' to the env gene on the HTLV-III genome. The presence of antibodies to p27 in virus-exposed individuals indicated that this gene is functional in the natural host.
- Subjects :
- Acquired Immunodeficiency Syndrome microbiology
Amino Acid Sequence
Animals
Antibody Formation
Deltaretrovirus genetics
Electrophoresis, Polyacrylamide Gel
Haplorhini microbiology
Humans
Male
Molecular Weight
Repetitive Sequences, Nucleic Acid
Acquired Immunodeficiency Syndrome immunology
Antibodies, Viral immunology
Antigens, Viral immunology
Deltaretrovirus immunology
Subjects
Details
- Language :
- English
- ISSN :
- 0036-8075
- Volume :
- 230
- Issue :
- 4727
- Database :
- MEDLINE
- Journal :
- Science (New York, N.Y.)
- Publication Type :
- Academic Journal
- Accession number :
- 2997921
- Full Text :
- https://doi.org/10.1126/science.2997921