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Cardiac and Pericardial 18 F-FDG Uptake on Oncologic PET/CT: Comparison with Echocardiographic Findings.
- Source :
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Journal of cardiovascular imaging [J Cardiovasc Imaging] 2018 Jun; Vol. 26 (2), pp. 93-102. Date of Electronic Publication: 2018 Jun 25. - Publication Year :
- 2018
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Abstract
- Background: Interpretation of cardiac uptake on 18-fluorodeoxyglucose positron emission tomography/computed tomography ( <superscript>18</superscript> F-FDG PET/CT) is often confounded by intense physiological FDG uptake and numerous benign conditions. The aim of the study was to describe the echocardiographic features in concordance with cardiac and pericardial <superscript>18</superscript> F-FDG uptake on whole-body oncology PET/CT.<br />Methods: We enrolled 43 consecutive patients (34 solid tumors, 8 lymphomas and 1 leukemia) who were newly diagnosed with non-cardiac malignancy showing incidental cardiac or pericardial <superscript>18</superscript> F-FDG uptake on PET/CT and underwent transthoracic Doppler echocardiography (TTE) within 1 month of PET/CT. The maximum standardized uptake (SUV <subscript>max</subscript> ) of all lesions was measured.<br />Results: Fifty-six <superscript>18</superscript> F-FDG uptake lesions (32 pericardium, 7 myocardium, 9 cardiac chambers and 8 great vessels) were found, and pericardial effusion was the most common echocardiographic finding (22/43, 51.2%) among study population. Pericardial FDG uptake was shown as pericardial effusion (68.8%), intrapericardial echogenic materials (31.3%), pericardial thickening (28.1%), hyperechogenicity of myopericardium (18.8%), and restricted sliding movement or constrictive pericarditis (15.6%) on TTE. Lesions with regional wall motion abnormality ( p = 0.004) or constrictive pericarditis ( p = 0.021) had significantly higher mean SUV <subscript>max</subscript> than those without. Myocardial FDG uptake demonstrated pericardial effusion (57.1%), regional wall motion abnormality (57.1%), and increased myocardial wall thickness (42.9%). All cardiac chamber FDG uptakes showed intracardiac mass on TTE.<br />Conclusions: Cardiac or pericardial <superscript>18</superscript> F-FDG uptake on oncology PET/CT shows characteristic echocardiographic features according to which heart sites are involved.<br />Competing Interests: Conflict of Interest: The authors have no financial conflicts of interest.
Details
- Language :
- English
- ISSN :
- 2586-7296
- Volume :
- 26
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of cardiovascular imaging
- Publication Type :
- Academic Journal
- Accession number :
- 29971271
- Full Text :
- https://doi.org/10.4250/jcvi.2018.26.e10