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A Case of Palpitations Due to T-Wave Oversensing Caused by Sacubitril/Valsartan.
- Source :
-
The Canadian journal of cardiology [Can J Cardiol] 2018 Aug; Vol. 34 (8), pp. 1089.e1-1089.e3. Date of Electronic Publication: 2018 Apr 05. - Publication Year :
- 2018
-
Abstract
- A 58-year-old man with previous mitral/aortic mechanical-valve replacement, aortic root repair, and coronary disease developed severe left-ventricular dysfunction following AV-node ablation/single-chamber pacemaker implantation for management of atrial fibrillation. He then underwent an upgrade to cardiac resynchronization therapy with a defibrillator. To manage his heart failure better, angiotensin-receptor blocker therapy was changed to sacubitril/valsartan, after which symptomatic palpitations with T-wave oversensing occurred. The resolved T-wave oversensing and palpitations stopped upon discontinuation of sacubitril/valsartan and recurred upon rechallenge, requiring a switch back to valsartan monotherapy. Our report presents the first known case of T-wave oversensing due to sacubitril/valsartan.<br /> (Crown Copyright © 2018. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Angiotensin Receptor Antagonists adverse effects
Arrhythmias, Cardiac physiopathology
Biphenyl Compounds
Drug Combinations
Heart Failure physiopathology
Humans
Male
Middle Aged
Valsartan
Aminobutyrates adverse effects
Arrhythmias, Cardiac chemically induced
Electrocardiography
Heart Failure drug therapy
Heart Rate drug effects
Stroke Volume physiology
Tetrazoles adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1916-7075
- Volume :
- 34
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- The Canadian journal of cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 29960804
- Full Text :
- https://doi.org/10.1016/j.cjca.2018.03.019