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Female Sex is Associated With Poor Health-related Quality of Life in Children at 12 Months Post-Hematopoietic Cell Transplantation.
- Source :
-
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2019 Apr; Vol. 41 (3), pp. 233-237. - Publication Year :
- 2019
-
Abstract
- To study the factors associated with poorer health-related quality of life at 1-year post-allogeneic hematopoietic cell transplantation (alloHCT), a secondary analysis of a prospective feasibility study was performed. Pediatric Quality of Life Inventory questionnaires were collected in 76 children undergoing alloHCT at baseline (within 30 d before transplantation), day 100, 6 months, and 12 months posttransplantation. The global score improved post-HCT (baseline: 67.1, 12 mo: 76.6). Females (odds ratio, 6.5; 95% confidence interval, 1.002-42.17; P=0.04) and patients with low baseline scores (odds ratio, 7.2; 95% confidence interval, 1.07-48.63; P=0.04) had lower scores at 12 months post-HCT and suggest a target group for early interventions such as physical exercise, stress management, and cognitive behavior therapy.
- Subjects :
- Child
Cognitive Behavioral Therapy
Exercise
Feasibility Studies
Female
Humans
Male
Prognosis
Prospective Studies
Stress, Psychological therapy
Surveys and Questionnaires
Transplantation, Homologous
Hematopoietic Stem Cell Transplantation methods
Hematopoietic Stem Cell Transplantation psychology
Quality of Life psychology
Sex Factors
Subjects
Details
- Language :
- English
- ISSN :
- 1536-3678
- Volume :
- 41
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of pediatric hematology/oncology
- Publication Type :
- Academic Journal
- Accession number :
- 29923857
- Full Text :
- https://doi.org/10.1097/MPH.0000000000001239