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Epidemiology of fungaemia in Sweden: A nationwide retrospective observational survey.
- Source :
-
Mycoses [Mycoses] 2018 Oct; Vol. 61 (10), pp. 777-785. Date of Electronic Publication: 2018 Jul 18. - Publication Year :
- 2018
-
Abstract
- Objectives: To identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates to identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates in Sweden.<br />Methods: The study was a retrospective, observational nationwide laboratory-based surveillance for fungaemia and fungal meningitis and was conducted from September 2015 to August 2016.<br />Results: In total, 488 Candida blood culture isolates were obtained from 471 patients (58% males). Compared to our previous study, the incidence of candidaemia has increased from 4.2/100 000 (2005-2006) to 4.7/100 000 population/year (2015-2016). The three most common Candida spp. isolated from blood cultures were Candida albicans (54.7%), Candida glabrata (19.7%) and species in the Candida parapsilosis complex (9.4%). Candida resistance to fluconazole was 2% in C. albicans and between 0% and 100%, in non-albicans species other than C. glabrata and C. krusei. Resistance to voriconazole was rare, except for C. glabrata, C. krusei and C. tropicalis. Resistance to anidulafungin was 3.8% while no Candida isolate was resistant to amphotericin B.<br />Conclusions: We report an overall increase in candidaemia but a minor decrease of C. albicans while C. glabrata and C. parapsilosis remain constant over this 10-year period.<br /> (© 2018 Blackwell Verlag GmbH.)
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Antifungal Agents pharmacology
Candida drug effects
Candidemia etiology
Child
Child, Preschool
Drug Resistance, Fungal
Female
Humans
Incidence
Infant
Infant, Newborn
Male
Meningitis, Fungal epidemiology
Meningitis, Fungal etiology
Microbial Sensitivity Tests
Middle Aged
Retrospective Studies
Sweden epidemiology
Young Adult
Candida classification
Candida isolation & purification
Candidemia epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1439-0507
- Volume :
- 61
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Mycoses
- Publication Type :
- Academic Journal
- Accession number :
- 29920785
- Full Text :
- https://doi.org/10.1111/myc.12816