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Emerixanthone E, a new xanthone derivative from deep sea fungus Emericella sp SCSIO 05240.
- Source :
-
Natural product research [Nat Prod Res] 2019 Jul; Vol. 33 (14), pp. 2088-2094. Date of Electronic Publication: 2018 Jun 17. - Publication Year :
- 2019
-
Abstract
- The marine fungus Emericella sp was isolated from the deep sea sediments. The fungus was identified by its morphology and ITS region. A new emerixanthone E ( 1 ) together with four ( 2-5 ) known emodin derivatives were isolated from the metabolites of the fungus Emericella SCSIO05240. The structures were elucidated on the basis of NMR spectroscopic analysis and mass spectrometry. The biological properties of those compounds ( 1-5 ) were explored for antimicrobial, antifungal and antitumor activity.
- Subjects :
- Anti-Bacterial Agents chemistry
Antifungal Agents chemistry
Antineoplastic Agents chemistry
Cell Line, Tumor
Drug Evaluation, Preclinical methods
Emericella genetics
Emericella isolation & purification
Emodin chemistry
Humans
Magnetic Resonance Spectroscopy
Molecular Structure
Seawater microbiology
Xanthones isolation & purification
Xanthones pharmacology
Anti-Bacterial Agents pharmacology
Antifungal Agents pharmacology
Antineoplastic Agents pharmacology
Emericella chemistry
Xanthones chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1478-6427
- Volume :
- 33
- Issue :
- 14
- Database :
- MEDLINE
- Journal :
- Natural product research
- Publication Type :
- Academic Journal
- Accession number :
- 29911443
- Full Text :
- https://doi.org/10.1080/14786419.2018.1487966