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Myopericytoma in an unusual location.
- Source :
-
Dermatology online journal [Dermatol Online J] 2018 Apr 15; Vol. 24 (4). Date of Electronic Publication: 2018 Apr 15. - Publication Year :
- 2018
-
Abstract
- Myopericytoma is a soft-tissue tumor of perivascular cells (pericytes). It is slow-growing, usually asymptomatic, and generally benign, although a malignant variant has been described. The etiology is unknown, but it has been associated with local trauma. The most common location is on the distal extremities. Histologically, it is characterized by a well-circumscribed, non-encapsulated proliferation of spindle shaped cells similar to myofibroblasts with oval nuclei and eosinophilic cytoplasm, arranged in perivascular concentric rings. There are few mitoses and no necrosis is reported. The immunohistochemical analysis is positive for smooth muscle actin and negative or weakly positive for desmin. A low Ki-67 proliferation index is typical. Treatment is surgical excision with free margins. Recurrences after adequate excision are uncommon. We describe a 48-year-old woman with a myopericytoma in an unusual location (next to the inner corner of her left eye) who was treated with surgical excision; there has been no recurrence after 5 years of follow up.
- Subjects :
- Eye
Facial Neoplasms pathology
Facial Neoplasms surgery
Female
Humans
Middle Aged
Myofibroma pathology
Myofibroma surgery
Pericytes pathology
Skin Neoplasms pathology
Skin Neoplasms surgery
Facial Neoplasms diagnosis
Myofibroma diagnosis
Neoplasm Recurrence, Local surgery
Skin Neoplasms diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1087-2108
- Volume :
- 24
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Dermatology online journal
- Publication Type :
- Academic Journal
- Accession number :
- 29906007