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Esophageal Motility after Extensive Circumferential Endoscopic Submucosal Dissection for Superficial Esophageal Cancer.
- Source :
-
Digestion [Digestion] 2018; Vol. 98 (3), pp. 153-160. Date of Electronic Publication: 2018 Jun 05. - Publication Year :
- 2018
-
Abstract
- Background/aims: Endoscopic submucosal dissection (ESD) for superficial esophageal cancer is sometimes extensive, and in our experience, patients not infrequently present with dysphagia after ESD even in the absence of esophageal stricture. The aim of this study was to evaluate esophageal motility using high-resolution manometry (HRM) in patients with and without dysphagia after extensive circumferential ESD.<br />Methods: HRM was performed in a total of 52 patients who had undergone ESD for superficial esophageal cancer and a mucosal defect after ESD exceeded more than two-thirds of the esophageal circumference. The frequency and type of esophageal dysmotility and the relationship between esophageal motility and dysphagia were evaluated.<br />Results: Esophageal dysmotility was observed in 13 patients (25%): jackhammer esophagus in 4, esophagogastric junction outflow obstruction in 4, absent contractility in 2, and distal esophageal spasm, ineffective esophageal motility, and fragmented peristalsis in 1 patient each. Of the 22 patients with dysphagia after ESD, 9 (41%) had esophageal dysmotility. Of the 30 patients without dysphagia after ESD, 4 (13%) had esophageal dysmotility. The relationship between dysmotility and dysphagia was significant (p = 0.025).<br />Conclusions: Esophageal dysmotility exists in approximately one-quarter of patients after extensive circumferential ESD, which is associated with dysphagia in the absence of esophageal stricture.<br /> (© 2018 S. Karger AG, Basel.)
- Subjects :
- Aged
Aged, 80 and over
Dilatation instrumentation
Dilatation methods
Endoscopic Mucosal Resection methods
Esophageal Motility Disorders diagnosis
Esophageal Motility Disorders etiology
Esophageal Motility Disorders therapy
Esophageal Mucosa pathology
Esophageal Mucosa surgery
Esophageal Neoplasms pathology
Esophagoscopy methods
Female
Humans
Male
Manometry methods
Middle Aged
Peristalsis
Postoperative Complications etiology
Postoperative Complications therapy
Endoscopic Mucosal Resection adverse effects
Esophageal Motility Disorders epidemiology
Esophageal Neoplasms surgery
Esophagoscopy adverse effects
Postoperative Complications epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1421-9867
- Volume :
- 98
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Digestion
- Publication Type :
- Academic Journal
- Accession number :
- 29870972
- Full Text :
- https://doi.org/10.1159/000487751