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Long-term ingestion of guar gum is not toxic in patients with noninsulin-dependent diabetes mellitus.
- Source :
-
The American journal of clinical nutrition [Am J Clin Nutr] 1985 May; Vol. 41 (5), pp. 891-4. - Publication Year :
- 1985
-
Abstract
- The use of diets rich in unabsorbable carbohydrate ("fiber") has been advocated for the treatment of noninsulin-dependent diabetes mellitus (NIDDM). The soluble viscous fibers such as guar gum are most effective in normalizing carbohydrate intolerance in such patients; particulate fibers such as cellulose have little or no effect. While the latter are known to affect many aspects of nutrition when consumed in great quantity, little is known of the toxicity of guar gum. Eight adults with NIDDM are reported here who consumed at least 30 grams of guar gum for at least 16 weeks without any change in hematologic, hepatic, or renal function. Serologic screening revealed no change in lipid, protein or mineral metabolism, and no change in electrolyte balance. It is concluded that consumption of 30 grams of guar gum per day for prolonged periods is without serious consequences.
- Subjects :
- Blood Cells drug effects
Blood Coagulation drug effects
Diabetes Mellitus, Type 2 blood
Dietary Fiber therapeutic use
Female
Food, Fortified
Galactans therapeutic use
Humans
Male
Mannans therapeutic use
Middle Aged
Plant Gums
Prospective Studies
Time Factors
Diabetes Mellitus, Type 2 diet therapy
Dietary Fiber toxicity
Galactans toxicity
Mannans toxicity
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9165
- Volume :
- 41
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- The American journal of clinical nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 2986444
- Full Text :
- https://doi.org/10.1093/ajcn/41.5.891