Back to Search
Start Over
Ureaplasma and Mycoplasma in kidney allograft recipients-A case series and review of the literature.
- Source :
-
Transplant infectious disease : an official journal of the Transplantation Society [Transpl Infect Dis] 2018 Oct; Vol. 20 (5), pp. e12937. Date of Electronic Publication: 2018 Jun 15. - Publication Year :
- 2018
-
Abstract
- Ureaplasma urealyticum and Mycoplasma hominis are common inhabitants of the human genital tract. Increasingly, serious and sometimes fatal infections in immunocompromised hosts have been reported, highlighting their pathogenic potential. We reviewed the clinical impact of positive Ureaplasma spp. and Mycoplasma spp. urine cultures in 10 renal allograft recipients who presented with sterile leukocyturia. Five recipients remained asymptomatic. Five patients were symptomatic with dysuria or pain at the graft site. Three patients developed biopsy-proven acute graft pyelonephritis with graft dysfunction. One of these patients additionally showed a renal abscess as demonstrated by magnetic resonance imaging (MRI). All were successfully treated. A literature search revealed a substantial number of case reports with severe and sometimes fatal Ureaplasma spp. or Mycoplasma spp. infections in immunocompromised patients. Colonization rate is high in renal transplant patients. A subset of patients is at risk for invasive disease.<br /> (© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
- Subjects :
- Adult
Allografts immunology
Allografts microbiology
Allografts pathology
Biopsy
Female
Graft Rejection immunology
Graft Rejection microbiology
Graft Rejection pathology
Graft Rejection prevention & control
Humans
Immunocompromised Host
Immunosuppression Therapy adverse effects
Male
Middle Aged
Mycoplasma Infections microbiology
Mycoplasma hominis pathogenicity
Ureaplasma Infections microbiology
Ureaplasma urealyticum pathogenicity
Urinary Tract Infections microbiology
Young Adult
Kidney Transplantation adverse effects
Mycoplasma Infections epidemiology
Mycoplasma hominis isolation & purification
Ureaplasma Infections epidemiology
Ureaplasma urealyticum isolation & purification
Urinary Tract Infections epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1399-3062
- Volume :
- 20
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Transplant infectious disease : an official journal of the Transplantation Society
- Publication Type :
- Academic Journal
- Accession number :
- 29856498
- Full Text :
- https://doi.org/10.1111/tid.12937