Back to Search
Start Over
Effectiveness of Disease-Specific Cognitive Behavioral Therapy on Anxiety, Depression, and Quality of Life in Youth With Inflammatory Bowel Disease: A Randomized Controlled Trial.
- Source :
-
Journal of pediatric psychology [J Pediatr Psychol] 2018 Oct 01; Vol. 43 (9), pp. 967-980. - Publication Year :
- 2018
-
Abstract
- Objective: To evaluate the effectiveness of a disease-specific cognitive behavioral therapy (CBT) protocol on anxiety and depressive symptoms and health-related quality of life (HRQOL) in adolescents and young adults with inflammatory bowel disease (IBD).<br />Method: A parallel group randomized controlled trial was conducted in 6 centers of (pediatric) gastroenterology. Included were 70 patients and young adults (10-25 years) with IBD and subclinical anxiety and/or depressive symptoms. Patients were randomized into 2 groups, stratified by center: (a) standard medical care (care-as-usual [CAU]) plus disease-specific manualized CBT (Primary and Secondary Control Enhancement Training for Physical Illness; PASCET-PI), with 10 weekly sessions, 3 parent sessions, and 3 booster sessions (n = 37), or (b) CAU only (n = 33). Primary analysis concerned the reliable change in anxiety and depressive symptoms after 3 months (immediate posttreatment assessment). Exploratory analyses concerned (1) the course of anxiety and depressive symptoms and HRQOL in subgroups based on age, and (2) the influence of age, gender, and disease type on the effect of the PASCET-PI.<br />Results: Overall, all participants improved significantly in their anxiety and depressive symptoms and HRQOL, regardless of group, age, gender, and disease type. Primary chi-square tests and exploratory linear mixed models showed no difference in outcomes between the PASCET-PI (n = 35) and the CAU group (n = 33).<br />Conclusions: In youth with IBD and subclinical anxiety and/or depressive symptoms, preliminary results of immediate post-treatment assessment indicated that a disease-specific CBT added to standard medical care did not perform better than standard medical care in improving psychological symptoms or HRQOL. ClinicalTrials.gov: NCT02265588.
- Subjects :
- Adolescent
Adult
Anxiety Disorders complications
Child
Depressive Disorder complications
Female
Humans
Inflammatory Bowel Diseases complications
Male
Treatment Outcome
Young Adult
Anxiety Disorders therapy
Cognitive Behavioral Therapy methods
Depressive Disorder therapy
Inflammatory Bowel Diseases psychology
Quality of Life psychology
Subjects
Details
- Language :
- English
- ISSN :
- 1465-735X
- Volume :
- 43
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Journal of pediatric psychology
- Publication Type :
- Academic Journal
- Accession number :
- 29850915
- Full Text :
- https://doi.org/10.1093/jpepsy/jsy029