[Effect of the method of measurement on the interpretation of renal clearance].

The concept of renal clearance measured during steady-state conditions includes the effect of filtration and secretion as well as urine flow. On the other hand, renal clearance, as used in nuclear medicine, only describes the effect of filtration and secretion. A way for determining steady-state renal clearance with a bolus injection technique is described. Steady-state renal clearance reflects the efficiency of filtration and secretion, urine flow, and the steady-state chemical potentials in the kidneys.